Linked Life Data

9172708

Source:http://linkedlifedata.com/resource/pubmed/id/9172708

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1997-5-30
pubmed:abstractText
The present study compared alterations of event-related brain potentials (ERPs) in subgroups of chronic alcoholics with different complications during alcohol withdrawal. Twenty alcoholics with only mild to moderate alcohol withdrawal symptoms, two groups of alcoholics with histories of either delirium tremens (n = 9) or alcohol hallucinosis (n = 13), and a control group of 38 nonalcoholics were examined. Patients were tested in unmedicated state and not earlier than 14 days after drinking cessation. An auditory Oddball paradigm and a visual Letter Matching paradigm were used as cognitive tasks. In the auditory task, all alcoholic groups exhibited delayed N200 and P300 latencies and a reduced P300 amplitude as compared to nonalcoholics. In the visual task, only P300 amplitude was significantly diminished. Patients having suffered from delirium tremens or alcohol hallucinosis showed greater Oddball P300 amplitudes than alcoholics with uncomplicated withdrawal syndrome. Furthermore, delirium and hallucinosis patients differed in their ERPs, with hallucinosis patients showing an earlier P300 peak in both the auditory Oddball and the Letter Matching task. It is concluded that changes in ERPs during abstinence might reflect specific neurophysiological dysfunctions in alcoholics prone to different alcohol-related psychoses.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-3223
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
873-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
ERP changes in alcoholics with and without alcohol psychosis.
pubmed:affiliation
Psychiatric Hospital, Ludwig-Maximilians University, Munich, Germany.
pubmed:publicationType
Journal Article, Comparative Study