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pubmed-article:9170297pubmed:abstractTextA methanol extract of leaves and twigs from Ardisia iwahigensis demonstrated toxicity toward brine shrimp as well as LNCaP, ZR-75-1, and Lu1 human cancer cells in culture. A novel alkenylphenol, (Z)-1,16-bis(3-hydroxy-5-methoxyphenyl)-10-hexadecene-1,15-dione (ardisenone) (1), was isolated from the extract by bioassay-directed fractionation. This compound demonstrated moderate cytotoxicity against BC1, Lu1, Col2, KB, KB-V1, and LNCaP cell lines.lld:pubmed
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pubmed-article:9170297pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:9170297pubmed:articleTitleIsolation and structure elucidation of ardisenone: a new, cytotoxic alkenylphenol from Ardisia iwahigensis.lld:pubmed
pubmed-article:9170297pubmed:affiliationDepartment of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago 60612, USA.lld:pubmed
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