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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1997-7-3
|
| pubmed:abstractText |
A methanol extract of leaves and twigs from Ardisia iwahigensis demonstrated toxicity toward brine shrimp as well as LNCaP, ZR-75-1, and Lu1 human cancer cells in culture. A novel alkenylphenol, (Z)-1,16-bis(3-hydroxy-5-methoxyphenyl)-10-hexadecene-1,15-dione (ardisenone) (1), was isolated from the extract by bioassay-directed fractionation. This compound demonstrated moderate cytotoxicity against BC1, Lu1, Col2, KB, KB-V1, and LNCaP cell lines.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0163-3864
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
60
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
533-5
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9170297-Animals,
pubmed-meshheading:9170297-Anisoles,
pubmed-meshheading:9170297-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:9170297-Artemia,
pubmed-meshheading:9170297-Drug Screening Assays, Antitumor,
pubmed-meshheading:9170297-Humans,
pubmed-meshheading:9170297-Magnetic Resonance Spectroscopy,
pubmed-meshheading:9170297-Plant Extracts,
pubmed-meshheading:9170297-Plants, Medicinal,
pubmed-meshheading:9170297-Spectrophotometry, Infrared,
pubmed-meshheading:9170297-Tumor Cells, Cultured
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Isolation and structure elucidation of ardisenone: a new, cytotoxic alkenylphenol from Ardisia iwahigensis.
|
| pubmed:affiliation |
Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago 60612, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|