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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1997-7-30
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pubmed:abstractText |
The purpose of this study was to assess the feasibility of imaging of bladder cancer with fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) scanning. We studied 12 patients with histologically proven bladder cancer who had undergone surgical procedures and/or radiotherapy. Retrograde irrigation of the urinary bladder with 1000-3710 ml saline was performed during nine of the studies. Dynamic and static PET images were obtained, and standardized uptake value images were reconstructed. FDG-PET scanning was true-positive in eight patients (66.7%), but false-negative in four (33.3%). Of 20 organs with tumor mass lesions confirmed pathologically or clinically, 16 (80%) were detected by FDG-PET scanning. FDG-PET scanning detected all of 17 distant metastatic lesions and two of three proven regional lymph node metastases. FDG-PET was also capable of differentiating viable recurrent bladder cancer from radiation-induced alterations in two patients. In conclusion, these preliminary data indicate the feasibility of FDG-PET imaging in patients with bladder cancer, although a major remaining pitfall is intense FDG accumulation in the urine.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0340-6997
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
615-20
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9169567-Carcinoma, Transitional Cell,
pubmed-meshheading:9169567-Deoxyglucose,
pubmed-meshheading:9169567-Feasibility Studies,
pubmed-meshheading:9169567-Female,
pubmed-meshheading:9169567-Fluorine Radioisotopes,
pubmed-meshheading:9169567-Fluorodeoxyglucose F18,
pubmed-meshheading:9169567-Humans,
pubmed-meshheading:9169567-Lymphatic Metastasis,
pubmed-meshheading:9169567-Male,
pubmed-meshheading:9169567-Middle Aged,
pubmed-meshheading:9169567-Tomography, Emission-Computed,
pubmed-meshheading:9169567-Urinary Bladder Neoplasms
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pubmed:year |
1997
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pubmed:articleTitle |
Preliminary assessment of fluorine-18 fluorodeoxyglucose positron emission tomography in patients with bladder cancer.
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pubmed:affiliation |
Department of Internal Medicine, Division of Nuclear Medicine, The University of Michigan Medical Center, Ann Arbor, Michigan, USA.
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pubmed:publicationType |
Journal Article
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