rdf:type |
|
lifeskim:mentions |
umls-concept:C0007131,
umls-concept:C0030705,
umls-concept:C0038952,
umls-concept:C0205179,
umls-concept:C0205265,
umls-concept:C0205420,
umls-concept:C0332293,
umls-concept:C0443252,
umls-concept:C0580822,
umls-concept:C1274040,
umls-concept:C1517927,
umls-concept:C1519810,
umls-concept:C1547300,
umls-concept:C1548760,
umls-concept:C1550594,
umls-concept:C1559154
|
pubmed:issue |
2
|
pubmed:dateCreated |
2006-9-26
|
pubmed:abstractText |
Patients with locally advanced, initially unresectable non-small cell lung cancer (NSCLC) have a median survival time of 9 to 11 months, a 2-year survival rate of 13%, and a long-term survival rate of 5% to 7% when treated with radical thoracic radiation alone. Because of the preclinical radiosensitizing capabilities of 5-fluorouracil and cisplatin and the therapeutic synergy of etoposide and cisplatin, we combined these agents with full-dose radical thoracic radiation to determine the feasibility and efficacy of this approach in locally advanced NSCLC.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1081-4442
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
99-105
|
pubmed:meshHeading |
pubmed-meshheading:9166507-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:9166507-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:9166507-Combined Modality Therapy,
pubmed-meshheading:9166507-Drug Therapy,
pubmed-meshheading:9166507-Female,
pubmed-meshheading:9166507-Humans,
pubmed-meshheading:9166507-Lung Neoplasms,
pubmed-meshheading:9166507-Male,
pubmed-meshheading:9166507-Pulmonary Surgical Procedures,
pubmed-meshheading:9166507-Radiotherapy, Adjuvant,
pubmed-meshheading:9166507-Survival Analysis,
pubmed-meshheading:9166507-Time Factors,
pubmed-meshheading:9166507-Treatment Outcome
|
pubmed:articleTitle |
Long-term survival results for patients with locally advanced, initially unresectable non-small cell lung cancer treated with aggressive concurrent chemoradiation.
|
pubmed:affiliation |
Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
|
pubmed:publicationType |
Journal Article,
Clinical Trial
|