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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1997-7-24
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pubmed:abstractText |
The prevalence of antibodies against cytomegalovirus (CMV) and the incidence of CMV infection were tested in 98 children aged 5 to 36 months who attended the day-care center of a University hospital in São Paulo. At the beginning of the study the overall prevalence of anti-CMV IgG antibodies was 44% (43/98). Saliva and/or urine samples were obtained from 38 of the 43 children that were seropositive at the beginning of the study for isolation of the virus, and 52.6% of these children were found to excrete CMV in one of the two materials. Among the 37 children that were initially seronegative from whom it was possible to obtain a new blood sample 6 to 12 months later, 22 (59.5%) presented seroconversion. The rate of viral excretion through urine or saliva from the children that seroconverted was 50%. These results indicate that CMV infection is frequent and occurs early among the children who attend this day-care center. However, controlled studies using molecular epidemiology techniques are needed to define more precisely the role of day-care centers in CMV dissemination.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0036-4665
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
165-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9163979-Antibodies, Viral,
pubmed-meshheading:9163979-Brazil,
pubmed-meshheading:9163979-Child, Preschool,
pubmed-meshheading:9163979-Child Day Care Centers,
pubmed-meshheading:9163979-Cytomegalovirus,
pubmed-meshheading:9163979-Cytomegalovirus Infections,
pubmed-meshheading:9163979-Female,
pubmed-meshheading:9163979-Humans,
pubmed-meshheading:9163979-Incidence,
pubmed-meshheading:9163979-Infant,
pubmed-meshheading:9163979-Male,
pubmed-meshheading:9163979-Prevalence
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pubmed:articleTitle |
Cytomegalovirus infection in a day-care center in the municipality of São Paulo.
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pubmed:affiliation |
Departamento de Medicina Tropical, Instituto Oswaldo Cruz, Fiocruz, Rio de Janeiro, Brasil.
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pubmed:publicationType |
Journal Article
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