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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1997-6-11
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pubmed:abstractText |
Chronic pulmonary hypertension is difficult to treat and despite the introduction of several therapeutic options, no single therapy is universally recommended. Nitric oxide has had some role clinically in improving pulmonary hemodynamics in this setting; however, basic investigation has not been performed in an appropriate large animal model of stable pulmonary hypertension. This study was designed to examine the effects of inhaled nitric oxide on pulmonary hemodynamics in the setting of a canine model of monocrotaline pyrrole-induced chronic pulmonary hypertension and used Fourier analysis for assessment of pulmonary vascular impedance.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-5223
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
113
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
849-57
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9159618-Animals,
pubmed-meshheading:9159618-Chronic Disease,
pubmed-meshheading:9159618-Disease Models, Animal,
pubmed-meshheading:9159618-Dogs,
pubmed-meshheading:9159618-Fourier Analysis,
pubmed-meshheading:9159618-Hemodynamics,
pubmed-meshheading:9159618-Hypertension, Pulmonary,
pubmed-meshheading:9159618-Lung,
pubmed-meshheading:9159618-Monocrotaline,
pubmed-meshheading:9159618-Nitric Acid,
pubmed-meshheading:9159618-Pulmonary Artery,
pubmed-meshheading:9159618-Regional Blood Flow,
pubmed-meshheading:9159618-Ventricular Function, Left
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pubmed:year |
1997
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pubmed:articleTitle |
Nitric oxide improves pulmonary vascular impedance, transpulmonary efficiency, and left ventricular filling in chronic pulmonary hypertension.
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pubmed:affiliation |
Department of Surgery, Duke University Medical Center, Durham, N.C, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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