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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
|
pubmed:dateCreated |
1977-12-29
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pubmed:abstractText |
The decapeptide derivative, L-histidyl-L-seryl-L-aspartyl-L-alanyl-L-valyl-L-phenylalanyl-L-threonyl-L-aspartyl-L-asparaginyl-L-tyrosine methyl ester, corresponding to the N-terminal sequence of both porcine and chicken VIP was synthesized in solution, by the stepwise strategy. Its pharmacological properties resemble those of VIP itself, but with a much lower potency, comparable to that of peptides with C-terminal sequences. The presence of two independent sequences carrying similar instructions was recognized in VIP.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0022-2623
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
20
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1461-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:915906-Amino Acid Sequence,
pubmed-meshheading:915906-Animals,
pubmed-meshheading:915906-Blood Pressure,
pubmed-meshheading:915906-Dogs,
pubmed-meshheading:915906-Gastrointestinal Hormones,
pubmed-meshheading:915906-Guinea Pigs,
pubmed-meshheading:915906-Muscle, Smooth,
pubmed-meshheading:915906-Muscle Contraction,
pubmed-meshheading:915906-Peptide Fragments,
pubmed-meshheading:915906-Rats,
pubmed-meshheading:915906-Regional Blood Flow,
pubmed-meshheading:915906-Vasoactive Intestinal Peptide
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pubmed:year |
1977
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pubmed:articleTitle |
Synthesis and pharmacological properties of the N-terminal decapeptide of the vasoactive intestinal peptide (VIP).
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.
|