Linked Life Data

9159061

Source:http://linkedlifedata.com/resource/pubmed/id/9159061

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-6-30
pubmed:abstractText
The most widely accepted point of view is that cells are endowed with the capacity to repair the primary lesions responsible for cancer induction. In radiobiology, this popular belief evolved from experiments of the same type as those that suggested the existence of sublethal radiation damage repair. The central problem with such data is that the cell-killing component of radiation damage may mask the effects associated with repair of precancerous lesions. The challenge is to separate the two processes that contribute to the observed tumor incidence after irradiation. using a recently developed stochastic model of radiation carcinogenesis allowing for cell death, we provide evidence that precancerous lesions are not subject to repair under certain experimental conditions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0025-5564
pubmed:author
pubmed:issnType
Print
pubmed:volume
142
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107-17
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Do cells repair precancerous lesions induced by radiation?
pubmed:affiliation
Huntsman Cancer Institute, Department of Oncological Sciences, University of Utah, Salt Lake City 84108, USA. yak@genetics.utah.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't