Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1997-6-9
|
pubmed:abstractText |
Few studies have quantified the effect of hypertension on survival in the hemodialysis population. We report the effect of hypertension on 1-year survival in 649 hemodialysis patients (89% black). In univariate analysis, hypertension was associated with improved 1-year survival (relative risk [RR], 0.48; P = 0.002 compared with normotensive patients). This effect of hypertension was mostly caused by the associated antihypertensive treatment because untreated hypertensive patients had survival rates equal to normotensive patients (RR, 0.87; P = 0.70). On the other hand, treated hypertensive patients fared better than normotensive patients (RR, 0.41; P = 0.0006). This was also true in multivariate analysis, in which antihypertensive treatment was associated with reduced RR (RR, 0.55; P = 0.02) whereas the level of blood pressure per se was insignificant (RR, 0.99; P = 0.63 per 1 mm Hg increase in predialysis mean arterial pressure). Other factors of significance in multivariate analysis included age (RR, 1.03/y; P = 0.0004), serum albumin (RR, 0.38/g; P = 0.002), and diabetes mellitus (RR, 1.58; P = 0.06). Our study suggests that antihypertensive treatment has a favorable effect on survival in the hemodialysis population irrespective of the level of blood pressure control.
|
pubmed:commentsCorrections | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0272-6386
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
28
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
737-40
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9158213-Antihypertensive Agents,
pubmed-meshheading:9158213-Female,
pubmed-meshheading:9158213-Follow-Up Studies,
pubmed-meshheading:9158213-Humans,
pubmed-meshheading:9158213-Hypertension,
pubmed-meshheading:9158213-Kidney Failure, Chronic,
pubmed-meshheading:9158213-Male,
pubmed-meshheading:9158213-Middle Aged,
pubmed-meshheading:9158213-Multivariate Analysis,
pubmed-meshheading:9158213-Proportional Hazards Models,
pubmed-meshheading:9158213-Renal Dialysis,
pubmed-meshheading:9158213-Risk Factors,
pubmed-meshheading:9158213-Survival Analysis
|
pubmed:year |
1996
|
pubmed:articleTitle |
Hypertension in the hemodialysis population: any relation to one-year survival?
|
pubmed:affiliation |
Department of Medicine, University of Mississippi Medical Center, Jackson 39216, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|