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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1997-6-2
|
| pubmed:abstractText |
Monoclonal antibodies (MAbs) to the fraction 1 (F1) protein of Yersinia pestis protected mice against fatal pneumonic as well as bubonic plague from wild-type F1+ organisms. The rare isolation of a virulent F1- isolate from surviving animals supports earlier studies suggesting that improved vaccines should consist of immunogens to protect against F1- variants. The high degree of protection with IgG MAb suggests that secretory IgA is not required for protection from pneumonic plague.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0002-9637
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
56
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
471-3
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:9158060-Animals,
pubmed-meshheading:9158060-Antibodies, Monoclonal,
pubmed-meshheading:9158060-Antibodies, Viral,
pubmed-meshheading:9158060-Bacterial Proteins,
pubmed-meshheading:9158060-Dose-Response Relationship, Immunologic,
pubmed-meshheading:9158060-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:9158060-Female,
pubmed-meshheading:9158060-Immunization, Passive,
pubmed-meshheading:9158060-Injections, Intraperitoneal,
pubmed-meshheading:9158060-Mice,
pubmed-meshheading:9158060-Plague,
pubmed-meshheading:9158060-Yersinia pestis
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Protection of mice from fatal bubonic and pneumonic plague by passive immunization with monoclonal antibodies against the F1 protein of Yersinia pestis.
|
| pubmed:affiliation |
U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, Maryland 21702-5011, USA.
|
| pubmed:publicationType |
Journal Article
|