| pubmed-article:9155006 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9155006 | lifeskim:mentions | umls-concept:C0085979 | lld:lifeskim |
| pubmed-article:9155006 | lifeskim:mentions | umls-concept:C0521119 | lld:lifeskim |
| pubmed-article:9155006 | lifeskim:mentions | umls-concept:C0026820 | lld:lifeskim |
| pubmed-article:9155006 | lifeskim:mentions | umls-concept:C0016976 | lld:lifeskim |
| pubmed-article:9155006 | lifeskim:mentions | umls-concept:C0441472 | lld:lifeskim |
| pubmed-article:9155006 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
| pubmed-article:9155006 | lifeskim:mentions | umls-concept:C0031584 | lld:lifeskim |
| pubmed-article:9155006 | lifeskim:mentions | umls-concept:C0851827 | lld:lifeskim |
| pubmed-article:9155006 | lifeskim:mentions | umls-concept:C1701901 | lld:lifeskim |
| pubmed-article:9155006 | pubmed:issue | 21 | lld:pubmed |
| pubmed-article:9155006 | pubmed:dateCreated | 1997-6-9 | lld:pubmed |
| pubmed-article:9155006 | pubmed:abstractText | The effects of phorbol 12,13 dibutyrate (PDBu) on the isometric tone of gall bladder strips isolated from guinea pig were investigated. PDBu caused the development of a contractile force at concentrations of 5 nM to 1 microM, which was abolished by staurosporine (30 nM). The contraction was completely inhibited in Ca2+-free solution and by pretreatment with verapamil (1 microM) or nifedipine (1 microM). A lower concentration of PDBu (1 nM) potentiated the contractile response to KCl: it increased the sensitivity, but not the reactivity of KCl-induced contraction. Ca2+-induced contraction in the solution with 15 mM KCl was significantly augmented by the pretreatment with 1 nM PDBu. However, PDBu (1 nM) affected neither Ca2+-induced contraction in the presence of Ca2+ ionophore A23187 (0.7 microM) and verapamil (1 microM) nor Ba2+-induced contraction in the Ca2+-free solution. These results suggest that activation of protein kinase C induces completely extracellular Ca2+-dependent contraction by activating the voltage-dependent Ca2+ channels in gall bladder of guinea pig. | lld:pubmed |
| pubmed-article:9155006 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9155006 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9155006 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9155006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9155006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9155006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9155006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9155006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9155006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9155006 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9155006 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9155006 | pubmed:issn | 0024-3205 | lld:pubmed |
| pubmed-article:9155006 | pubmed:author | pubmed-author:WakabayashiII | lld:pubmed |
| pubmed-article:9155006 | pubmed:author | pubmed-author:MasuiHH | lld:pubmed |
| pubmed-article:9155006 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9155006 | pubmed:volume | 60 | lld:pubmed |
| pubmed-article:9155006 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9155006 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9155006 | pubmed:pagination | PL 311-6 | lld:pubmed |
| pubmed-article:9155006 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:meshHeading | pubmed-meshheading:9155006-... | lld:pubmed |
| pubmed-article:9155006 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9155006 | pubmed:articleTitle | Extracellular Ca2+-dependent contractile action of phorbol 12,13-dibutyrate on gall bladder from guinea pig. | lld:pubmed |
| pubmed-article:9155006 | pubmed:affiliation | Department of Hygiene, Hyogo College of Medicine, Nishinomiya, Japan. | lld:pubmed |
| pubmed-article:9155006 | pubmed:publicationType | Journal Article | lld:pubmed |
