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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1997-6-10
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pubmed:abstractText |
A 2-month-old child with infantile hypophosphatasia had hypercalcemia (3.49 mmol/L (14 mg/dl)), nephrocalcinosis, and diminished bone mineral content. Hypercalcemia was corrected with calcitonin. Hypercalciuria and bone demineralization abated with chlorothiazide. Hypercalcemia is hypothesized to be related to normal bone resorption in conjunction with impaired bone mineralization. Chlorothiazide may alleviate this impairment.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-3476
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
130
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
825-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9152296-Bone Resorption,
pubmed-meshheading:9152296-Calcitonin,
pubmed-meshheading:9152296-Calcium,
pubmed-meshheading:9152296-Chlorothiazide,
pubmed-meshheading:9152296-Diuretics,
pubmed-meshheading:9152296-Female,
pubmed-meshheading:9152296-Humans,
pubmed-meshheading:9152296-Hypercalcemia,
pubmed-meshheading:9152296-Hypophosphatasia,
pubmed-meshheading:9152296-Infant,
pubmed-meshheading:9152296-Nephrocalcinosis,
pubmed-meshheading:9152296-Sodium Chloride Symporter Inhibitors
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pubmed:year |
1997
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pubmed:articleTitle |
Infantile hypophosphatasia: treatment options to control hypercalcemia, hypercalciuria, and chronic bone demineralization.
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pubmed:affiliation |
Department of Pediatrics, Children's Hospital Medical Center, Cincinnati, Ohio.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
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