Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1997-6-9
|
| pubmed:abstractText |
Age-related macular degeneration (AMD) is a genetically complex disorder. Tissue inhibitor of metalloproteinases-3 (TIMP3) on chromosome 22 has been identified as a gene that is mutated in Sosby's fundus dystrophy, an autosomal-dominant macular dystrophy that phenotypically resembles AMD. The purpose of this study was to determine whether TIMP3 is a major susceptibility gene for the AMD phenotype.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0146-0404
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
38
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1060-5
|
| pubmed:dateRevised |
2010-11-18
|
| pubmed:meshHeading |
pubmed-meshheading:9152225-Aged,
pubmed-meshheading:9152225-Aging,
pubmed-meshheading:9152225-Chromosome Mapping,
pubmed-meshheading:9152225-Genetic Linkage,
pubmed-meshheading:9152225-Haplotypes,
pubmed-meshheading:9152225-Humans,
pubmed-meshheading:9152225-Lod Score,
pubmed-meshheading:9152225-Macular Degeneration,
pubmed-meshheading:9152225-Pedigree,
pubmed-meshheading:9152225-Proteins,
pubmed-meshheading:9152225-Tissue Inhibitor of Metalloproteinase-3
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Exclusion of TIMP3 as a candidate locus in age-related macular degeneration.
|
| pubmed:affiliation |
Department of Ophthalmology, Duke University Medical Center, Durham, North Carolina, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|