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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1997-7-8
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pubmed:abstractText |
Immunohistologic studies were performed to identify the phenotype and distribution of neoplastic lymphocytes in the spleens of BLV-negative animals examined by PCR and diagnosed as having sporadic bovine leukosis. Tumor cells from three cases of sporadic bovine leukosis were identified as of B-cell lineage. Tumor cells from three additional cattle were identified as CD3+ CD4- CD8+, CD3+ CD4- CD8-, and CD3+ CD4- WC1+, respectively. The last case was diagnosed as a gamma/delta T-cell lymphoma. Differences in morphology proliferative characteristics were recognized between B- and T-cell type lymphomas. The tumor cells in B-cell type lymphoma were characterized as follows: medium or large in size, round or polymorphic nucleus with rough chromatin with some tumor cells containing a convoluted nucleus. These tumor cells of B-cell type lymphoma were present in the red pulp and periarteriolar lymphoid sheath. Tumor cells of the T-cell type lymphoma were uniformly smaller than B-cell type and present around arteries or replaced red pulp of the spleen.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0165-2427
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
283-90
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9151400-Animals,
pubmed-meshheading:9151400-Cattle,
pubmed-meshheading:9151400-Cattle Diseases,
pubmed-meshheading:9151400-Female,
pubmed-meshheading:9151400-Immunohistochemistry,
pubmed-meshheading:9151400-Immunophenotyping,
pubmed-meshheading:9151400-Lymph Nodes,
pubmed-meshheading:9151400-Lymphoma, B-Cell,
pubmed-meshheading:9151400-Lymphoma, T-Cell,
pubmed-meshheading:9151400-Male,
pubmed-meshheading:9151400-Spleen
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pubmed:year |
1997
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pubmed:articleTitle |
Further analysis of the phenotype and distribution of tumor cells in sporadic B-cell and T-cell lymphomas in the lymph node and spleen of cattle.
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pubmed:affiliation |
Department of Veterinary Pathology, Faculty of Agriculture, Iwate University, Morioka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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