Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1997-6-12
|
| pubmed:abstractText |
Whether or not genes are in an active or a repressed state in a cell depends on the relative effect of gene silencers and locus control regions (LCRs). Here, we suggest that these elements act as binary switches; the state that prevails (activated or repressed) probably depends on a competition between protein complex formation and the stability of the complexes formed at either of the two elements.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0968-0004
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
22
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
124-8
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:9149531-Animals,
pubmed-meshheading:9149531-Chromatin,
pubmed-meshheading:9149531-Drosophila,
pubmed-meshheading:9149531-Gene Expression Regulation,
pubmed-meshheading:9149531-Regulatory Sequences, Nucleic Acid,
pubmed-meshheading:9149531-Repressor Proteins,
pubmed-meshheading:9149531-Transcription, Genetic,
pubmed-meshheading:9149531-Transcription Factors
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Silencers and locus control regions: opposite sides of the same coin.
|
| pubmed:affiliation |
Laboratory of Molecular Embryology, NICHD, Bethesda, MD 20892, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review
|