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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1997-8-13
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pubmed:abstractText |
According to French rules for cadaver organ sharing, children with biliary atresia (BA) complicated with acute necrosis (ALN) can be registered on the waiting list for liver transplantation (LT) in a special intermediate grade urgent code. Over a 7 years period, 100 children have been submitted to elective LT for BA and 15 to urgent LT. Urgent procedures accounted for 25% of LT for BA in patients aged 0-2 years and 67% (8/12) in patients under 1 year of age. Children actuarial survival at 1, 12 and 48 months was respectively 66%, 60% and 60% versus 92%, 86% and 85%, deaths occurring earlier in the urgent group. Graft actuarial survival at 1, 12 and 48 months were 60%, 53% and 53% versus 85%, 77% and 76% (p < 0.05), respectively. Outcome of children and grafts after LT is not significantly different in BA cases and in other urgent indications, excluding retransplantations. In a LT program based on cadaver organ donation, allocation of in an urgent registration code to children with BA and ALN offers them more than 50% chance to escape death and does not result in wasting of grafts.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0040-8727
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
181
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
129-38
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9149347-Actuarial Analysis,
pubmed-meshheading:9149347-Age Factors,
pubmed-meshheading:9149347-Biliary Atresia,
pubmed-meshheading:9149347-Child, Preschool,
pubmed-meshheading:9149347-Female,
pubmed-meshheading:9149347-Graft Survival,
pubmed-meshheading:9149347-Humans,
pubmed-meshheading:9149347-Infant,
pubmed-meshheading:9149347-Liver,
pubmed-meshheading:9149347-Liver Transplantation,
pubmed-meshheading:9149347-Male,
pubmed-meshheading:9149347-Portoenterostomy, Hepatic,
pubmed-meshheading:9149347-Postoperative Complications,
pubmed-meshheading:9149347-Survival Rate,
pubmed-meshheading:9149347-Treatment Outcome
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pubmed:year |
1997
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pubmed:articleTitle |
Urgent liver transplantation for biliary atresia: the experience in Bicêtre.
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pubmed:affiliation |
Service de Chirurgie Pédiatrique, Centre Hospitalier Universitaire Bicêtre, Faculté de Médecine Paris Sud, Université Paris 11, Le Kremlin Bicêtre, France.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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