|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0002475,
umls-concept:C0008838,
umls-concept:C0008976,
umls-concept:C0013089,
umls-concept:C0087111,
umls-concept:C0162458,
umls-concept:C0205179,
umls-concept:C0205195,
umls-concept:C0205390,
umls-concept:C0337810,
umls-concept:C0684249,
umls-concept:C1377913
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
1997-6-3
|
|
pubmed:abstractText |
In a previous FONICAP trial, the combination of doxorubicin (D) and cisplatin (P) yielded an objective response rate of 25% and a subjective response rate of 50% in patients with mesothelioma. In human mesothelioma cell lines, mitomycin (M) showed a synergic activity with P and in a recent randomized study, the combination of M and P showed slightly superior activity when compared with the PD regimen.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0008-543X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
79
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1897-902
|
|
pubmed:dateRevised |
2006-4-24
|
|
pubmed:meshHeading |
pubmed-meshheading:9149015-Adult,
pubmed-meshheading:9149015-Aged,
pubmed-meshheading:9149015-Antibiotics, Antineoplastic,
pubmed-meshheading:9149015-Antineoplastic Agents,
pubmed-meshheading:9149015-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:9149015-Bone Marrow,
pubmed-meshheading:9149015-Chest Pain,
pubmed-meshheading:9149015-Cisplatin,
pubmed-meshheading:9149015-Disease Progression,
pubmed-meshheading:9149015-Doxorubicin,
pubmed-meshheading:9149015-Dyspnea,
pubmed-meshheading:9149015-Feasibility Studies,
pubmed-meshheading:9149015-Female,
pubmed-meshheading:9149015-Humans,
pubmed-meshheading:9149015-Infusions, Intravenous,
pubmed-meshheading:9149015-Male,
pubmed-meshheading:9149015-Mesothelioma,
pubmed-meshheading:9149015-Middle Aged,
pubmed-meshheading:9149015-Mitomycins,
pubmed-meshheading:9149015-Neoplasm Staging,
pubmed-meshheading:9149015-Pleural Effusion, Malignant,
pubmed-meshheading:9149015-Pleural Neoplasms,
pubmed-meshheading:9149015-Remission Induction
|
|
pubmed:year |
1997
|
|
pubmed:articleTitle |
Combined cisplatin, doxorubicin, and mitomycin for the treatment of advanced pleural mesothelioma: a phase II FONICAP trial. Italian Lung Cancer Task Force.
|
|
pubmed:affiliation |
Division of Medical Oncology I, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Clinical Trial, Phase II
|
