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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1997-5-15
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pubmed:abstractText |
The concentration of phosphate in buffered saline irrigation solutions was evaluated for its effect upon the incidence of arterial thrombosis. A rabbit thrombosis model of combined intimal abrasion and twisted pedicle in the rabbit central ear artery was used. Higher concentrations of phosphate (20 mM) in normal saline yielded a lower thrombosis rate at 7 days postoperatively (50%) in comparison to 5 mM phosphate (89% thrombosis rate; P < 0.05). A standard phosphate-buffered salt solution (Dulbecco's; 9.5 mM phosphate with potassium, calcium, and magnesium salts) also had a high thrombosis rate (91%). This study demonstrates that subtle variations in the irrigation solution can have profound effects upon arterial thrombosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0738-1085
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
757-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:9148104-Animals,
pubmed-meshheading:9148104-Buffers,
pubmed-meshheading:9148104-Disease Models, Animal,
pubmed-meshheading:9148104-Ear,
pubmed-meshheading:9148104-Microsurgery,
pubmed-meshheading:9148104-Phosphates,
pubmed-meshheading:9148104-Rabbits,
pubmed-meshheading:9148104-Therapeutic Irrigation,
pubmed-meshheading:9148104-Thrombosis,
pubmed-meshheading:9148104-Vascular Patency
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pubmed:year |
1995
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pubmed:articleTitle |
Effect of phosphate concentration in buffered irrigating solutions on arterial thrombosis.
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pubmed:affiliation |
Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
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pubmed:publicationType |
Journal Article
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