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| pubmed-article:9143307 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
| pubmed-article:9143307 | lifeskim:mentions | umls-concept:C0162326 | lld:lifeskim |
| pubmed-article:9143307 | lifeskim:mentions | umls-concept:C0376315 | lld:lifeskim |
| pubmed-article:9143307 | lifeskim:mentions | umls-concept:C1881379 | lld:lifeskim |
| pubmed-article:9143307 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:9143307 | pubmed:dateCreated | 1997-6-4 | lld:pubmed |
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| pubmed-article:9143307 | pubmed:abstractText | Evolutionary associations of human and simian T-cell leukemia/lymphotropic viruses I and II (HTLV-I/II and STLV-I/II) are inferred from phylogenetic analysis of tax gene sequences. Samples studied consisted of a geographically diverse assemblage of viral strains obtained from 10 human subjects and 20 individuals representing 12 species of nonhuman primates. Sequence analyses identified distinct substitutions, which distinguished between viral types I and II, irrespective of host species. Phylogenetic reconstruction of nucleotide sequences strongly supported two major evolutionary groups corresponding to viral types I and II. With the type I lineage, clusters were composed of strains from multiple host species. A genetically diverse, monophyletic lineage consisting of eight new viral strains from several species of Asian macaques was identified. The second lineage consisted of a monophyletic assemblage of HTLV-II/STLV-II strains from Africa and the New World, including an isolate from a pygmy chimp (Pan paniscus) as an early divergence within the lineage. High levels of genetic variation among strains from Asian STLV-I macaque suggest the virus arose in Asia. Evidence of the origin of the type II virus is less clear, but diversity among HTLV-II variants from a single isolated population of Mbati villagers is suggestive but not proof of an African origin. | lld:pubmed |
| pubmed-article:9143307 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9143307 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9143307 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:9143307 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9143307 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9143307 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:9143307 | pubmed:issn | 0042-6822 | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:RosenLL | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:O'BrienS JSJ | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:FranchiniGG | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:DesrosiersR... | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:AnthonyRR | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:HervaRR | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:GireMM | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:GessainAA | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:HeneineWW | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:RichardsA LAL | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:McClurgJJ | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:SlatteryJ PJP | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:IskandriatiDD | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:PamungkasJJ | lld:pubmed |
| pubmed-article:9143307 | pubmed:author | pubmed-author:RivadeneiraEE | lld:pubmed |
| pubmed-article:9143307 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9143307 | pubmed:day | 28 | lld:pubmed |
| pubmed-article:9143307 | pubmed:volume | 231 | lld:pubmed |
| pubmed-article:9143307 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9143307 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9143307 | pubmed:pagination | 96-104 | lld:pubmed |
| pubmed-article:9143307 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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| pubmed-article:9143307 | pubmed:meshHeading | pubmed-meshheading:9143307-... | lld:pubmed |
| pubmed-article:9143307 | pubmed:year | 1997 | lld:pubmed |
| pubmed-article:9143307 | pubmed:articleTitle | The tax gene sequences form two divergent monophyletic lineages corresponding to types I and II of simian and human T-cell leukemia/lymphotropic viruses. | lld:pubmed |
| pubmed-article:9143307 | pubmed:affiliation | Basic Research Laboratory, National Cancer Institute, Bethesda, Maryland 20892, USA. | lld:pubmed |
| pubmed-article:9143307 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9143307 | lld:pubmed |
