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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1997-6-5
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pubmed:abstractText |
Intermittent claudication due to peripheral arterial occlusive disease (PAOD) is a common cause of pain and disability in the middle-aged. Clinical trials of the potent vasodilator prostaglandin E1 have been disappointing. This is the first report of a controlled clinical trial of AS-0:3, a novel prodrug of prostaglandin E1 incorporated into lipid microspheres that has been developed to improve delivery of the active compound to blood vessel walls.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0009-7322
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
6
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2298-302
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9142008-Aged,
pubmed-meshheading:9142008-Alprostadil,
pubmed-meshheading:9142008-Dose-Response Relationship, Drug,
pubmed-meshheading:9142008-Double-Blind Method,
pubmed-meshheading:9142008-Female,
pubmed-meshheading:9142008-Humans,
pubmed-meshheading:9142008-Intermittent Claudication,
pubmed-meshheading:9142008-Male,
pubmed-meshheading:9142008-Middle Aged,
pubmed-meshheading:9142008-Pain,
pubmed-meshheading:9142008-Placebos,
pubmed-meshheading:9142008-Prodrugs,
pubmed-meshheading:9142008-Quality of Life,
pubmed-meshheading:9142008-Walking
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pubmed:year |
1997
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pubmed:articleTitle |
Randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of AS-013, a prostaglandin E1 prodrug, in patients with intermittent claudication.
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pubmed:affiliation |
Ninewells Hospital and Medical School, Dundee, UK.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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