Linked Life Data

9137481

Source:http://linkedlifedata.com/resource/pubmed/id/9137481

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2B
pubmed:dateCreated
1997-5-21
pubmed:abstractText
ErbB2/neu protein (p185) expression was evaluated by ELISA in 115 breast cancer specimens. Distribution was subdivided in quartiles and showed a distinct behaviour in comparison with both clinico-biological parameters and clinical outcome. In particular, intermediate concentration groups showed a significantly better disease-free survival than the low and high concentration groups (p = 0.02). We classified the patients as "low risk" (64 samples with p185 concentrations between 2150 and 30000 U/mg of proteins) and "high risk" on the basis of the results of the multivariate analysis. The p185 grouped as described showed a significant relationship with the disease free survival in multivariate analysis. Although the data must be considered as preliminary, they suggest the possibility of identifying more appropriately the high risk patients through the biochemical determination of p185.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0250-7005
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1245-7
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:articleTitle
ErbB2 assay in breast cancer: possibly improved clinical information using a quantitative method.
pubmed:affiliation
Center for the Study of Biological Markers of Malignancy, Regional General Hospital, Venice, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't