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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1997-7-1
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pubmed:abstractText |
We have developed a simple, direct radioimmunoassay for progesterone in saliva. The correlation coefficient (r) between the direct assay and an extraction procedure was 0.92 (n = 65, P < 0.001), and the correlation between concurrent serum and salivary progesterone concentrations in the luteal phases of menstrual cycles of 48 women was 0.75 (P < 0.001). Whereas certain polystyrene and polyethylene vials and tubes were found to bind and remove up to 87% of the progesterone from saliva, other plastic and glass surfaces were satisfactory for the procedure. Intraassay and interassay CVs from values greater than 300 pmol/L were 12.0 and 12.4%, respectively. The assay sensitivity was 48 pmol/L. Collection of saliva is a more convenient and less invasive technique for frequent sample collection than phlebotomy, and is useful for monitoring ovulation and assessment of luteal function in women clinically.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0197-1522
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
149-63
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9134474-Adult,
pubmed-meshheading:9134474-Body Fluids,
pubmed-meshheading:9134474-Female,
pubmed-meshheading:9134474-Humans,
pubmed-meshheading:9134474-Male,
pubmed-meshheading:9134474-Menstrual Cycle,
pubmed-meshheading:9134474-Progesterone,
pubmed-meshheading:9134474-Protein Binding,
pubmed-meshheading:9134474-Radioimmunoassay,
pubmed-meshheading:9134474-Saliva,
pubmed-meshheading:9134474-Tritium
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pubmed:year |
1997
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pubmed:articleTitle |
Direct radioimmunoassay of progesterone in saliva.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, IL 60611, USA.
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pubmed:publicationType |
Journal Article
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