Linked Life Data

9131320

Source:http://linkedlifedata.com/resource/pubmed/id/9131320

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1997-6-26
pubmed:abstractText
It is becoming increasingly apparent that pyridoxine responsive homocystinuria patients are being missed by newborn screening programs. The possibility that screening for homocystine, rather than the methionine, might be more effective was investigated by comparing homocystine and methionine levels of non-responsive patients at diagnosis. The plasma methionine levels of 11 infants were much more abnormal than the homocystine levels. Urine homocystine was low or not detectable and always less than methionine. Therefore, methionine determination is much more effective than homocystine determination for newborn screening for homocystinuria. It seems that a second blood specimen at a later age may be required to find the pyridoxine responsive infants.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0378-3782
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
203-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Newborn screening for homocystinuria.
pubmed:affiliation
Department of Pediatrics, New York University Medical Center, NY 10016, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.