Linked Life Data

9128028

Source:http://linkedlifedata.com/resource/pubmed/id/9128028

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1997-7-11
pubmed:abstractText
We investigated antiemetic effect of clonidine in postoperative nausea and vomiting (PONV) after laparoscopic cholecystectomy. One hundred and fifty nine patients were female, and were ranged in age 20 to 60 years. The body mass index of the patients was less than 30, and duration of operation was within 120 minutes. All patients received general anesthesia combined with epidural analgesia. One hundred and fifty nine patients were randomly divided into three groups: control group (n = 53); epidural group (n = 53) which received clonidine 150 micrograms epidurally before incision, oral group (n = 53) which received clonidine 150 micrograms orally 60-90 min prior to arrival in the operating room. The overall incidence of PONV during the first 12 h postoperatively was smaller in epidural group (15.1%, P < 0.01) and in oral group (7.5%, P < 0.05) compared with control group (32.1%). The incidence of PONV during the first postoperative hour was significantly smaller in epidural group (3.8%, P < 0.01) and in oral group (3.8%, P < 0.01) compared with control group (18.9%). Postoperative analgesic requirement was not significantly different among the three groups. We conclude that oral or epidural clonidine decreased the incidence of early PONV after laparoscopic cholecystectomy.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0021-4892
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
538-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
[Effectiveness of clonidine in postoperative nausea and vomiting--epidural versus oral administration].
pubmed:affiliation
Department of Anesthesia, Izinkai Takeda General Hospital, Kyoto.
pubmed:publicationType
Journal Article, Clinical Trial, English Abstract, Randomized Controlled Trial