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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1997-4-21
|
| pubmed:abstractText |
We evaluated the usefulness of peripherally injected sonicated albumin microbubbles in transesophageal echo-Doppler cardiographic assessment of the left atrial appendage in 19 patients (age 61 +/- 19 [range 21 to 86] years; 12 [63%] women). Multiplane transesophageal echocardiography was performed before and after intravenous injection of sonicated albumin, and the left atrial appendage image and Doppler flow signal quality were assessed by a grading system of 0 to 3+ (0 = poor, 1 + = adequate, 2+ = good, and 3+ = excellent). Microbubbles appeared in the left atrium in 15 (79%) of 19 patients and completely opacified the left atrial appendage in 7 (37%) of 19 patients. Left atrial appendage maximal and minimal areas by planimetry were similar before and after contrast injection, although image quality improved in 13 (68%) of 19 patients (echocardiographic grade 1.8 +/- 0.6 vs 2.6 +/- 0.5, p< 0.001). Similarly, left atrial appendage peak emptying and peak filling Doppler flow velocities did not change before and after contrast injection, although Doppler flow signal quality improved in 12 (63%) of 19 patients (Doppler grade 1.6 +/- 0.5 vs 2.1 +/- 0.8, p < 0.05). Overall, contrast injection improved left atrial appendage echocardiographic or Doppler quality in 16 (84%) of 19 patients. Thus peripheral vein injection of sonicated albumin microbubbles can improve the assessment of left atrial appendage structure and function by transesophageal echocardiography.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0002-8703
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
133
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
400-5
|
| pubmed:dateRevised |
2006-2-27
|
| pubmed:meshHeading |
pubmed-meshheading:9124160-Albumins,
pubmed-meshheading:9124160-Atrial Function, Left,
pubmed-meshheading:9124160-Blood Flow Velocity,
pubmed-meshheading:9124160-Contrast Media,
pubmed-meshheading:9124160-Echocardiography, Doppler,
pubmed-meshheading:9124160-Echocardiography, Transesophageal,
pubmed-meshheading:9124160-Female,
pubmed-meshheading:9124160-Heart Atria,
pubmed-meshheading:9124160-Humans,
pubmed-meshheading:9124160-Hypertrophy, Left Ventricular,
pubmed-meshheading:9124160-Injections, Intravenous,
pubmed-meshheading:9124160-Male,
pubmed-meshheading:9124160-Middle Aged,
pubmed-meshheading:9124160-Ventricular Dysfunction, Left
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Improved Doppler echocardiographic assessment of the left atrial appendage by peripheral vein injection of sonicated albumin microbubbles.
|
| pubmed:affiliation |
Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
|
| pubmed:publicationType |
Journal Article
|