Linked Life Data

9120620

Source:http://linkedlifedata.com/resource/pubmed/id/9120620

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1997-4-23
pubmed:abstractText
The authors report outcomes in 18 patients with arteriovenous malformations (AVMs) who were treated with gamma knife radiosurgery and in whom magnetic resonance (MR) imaging was obtained a mean of 14 years (range 8-23 years) after treatment and 10 years (range 4-17 years) after confirmed obliteration of the AVM. All patients were asymptomatic after radiosurgery and during the time of the study. In five patients (28%), cyst formation was observed that corresponded to the site of the obliterated AVM. Cyst formation and contrast enhancement on MR imaging could not be statistically correlated to the radiation dose. In 11 (61%) of the 18 patients, contrast enhancement that was not related to a recanalization of the nidus was observed in the target area. In three patients (17%), an increased T2-weighted signal was detected at the site of previous AVM; this was interpreted as gliosis or demyelination, which appeared to be dose dependent. The study illustrates that cyst formation, contrast enhancement, and an increased T2-weighted signal can be observed in asymptomatic patients in the area that was targeted for AVM radiosurgery up to 23 years after the procedure. The report provides new and essential information about long-term effects on normal tissue after radiosurgery and provides a basis for the interpretation of MR studies in the follow up of small AVMs treated by radiosurgery.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-3085
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
589-93
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Magnetic resonance imaging of obliterated arteriovenous malformations up to 23 years after radiosurgery.
pubmed:affiliation
Department of Neurosurgery, Karolinska Hospital, Stockholm, Sweden.
pubmed:publicationType
Journal Article