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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1997-4-24
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pubmed:databankReference |
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pubmed:abstractText |
The kdsA and kdsB genes from Chlamydia trachomatis encoding 3-deoxy-D-manno-octulosonate (KDO)-8-phosphate synthetase and CMP-KDO synthetase were identified by functional complementation of temperature-sensitive Salmonella typhimurium mutants, homology to known KDO-8-phosphate synthetase and CMP-KDO synthetase proteins, and in vitro enzyme activity. The kdsA gene was transcribed as part of a polycistronic mRNA with two downstream open reading frames (ORFs). One of these ORFs appeared to encode a membrane-anchored protein, while the second encoded a protein showing homology to the ATP-binding component of periplasmic binding protein-dependent ABC transporters. Transcription of kdsA and kdsB in C. trachomatis was evident within 4 h of initiation of the C. trachomatis infection process and continued throughout the chlamydial life cycle.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-1382060,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-2436232,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-2989246,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-3037377,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-3041230,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-3285782,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-3988347,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-6259128,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-6285137,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-6329717,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-6427112,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-6988389,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-7048004,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-7713886,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-8188348,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-8202093,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-8397187,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-8665464,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-8748024,
http://linkedlifedata.com/resource/pubmed/commentcorrection/9119498-8951811
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1527-30
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:9119498-Aldehyde-Lyases,
pubmed-meshheading:9119498-Amino Acid Sequence,
pubmed-meshheading:9119498-Base Sequence,
pubmed-meshheading:9119498-Chlamydia trachomatis,
pubmed-meshheading:9119498-Gene Expression Regulation, Bacterial,
pubmed-meshheading:9119498-Gene Expression Regulation, Developmental,
pubmed-meshheading:9119498-Molecular Sequence Data,
pubmed-meshheading:9119498-Nucleotidyltransferases,
pubmed-meshheading:9119498-Sequence Alignment
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pubmed:year |
1997
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pubmed:articleTitle |
Identification, characterization, and developmental regulation of Chlamydia trachomatis 3-deoxy-D-manno-octulosonate (KDO)-8-phosphate synthetase and CMP-KDO synthetase.
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pubmed:affiliation |
Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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