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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1997-4-22
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pubmed:abstractText |
Data from 30 elderly inpatients with major depression were analyzed to explore the relationship between subcortical hyperintensities (SH) on MRI and activities of daily living (ADLs). A comparison of subjects based on a median split of the severity of SH revealed that subjects with greater SH performed worse on both instrumental and physical ADLs. A hierarchical multiple regression revealed that age, depression severity, neuropsychological test performance, and SH variables accounted for a total of 53% of the variance in ADL functioning. Severity of SH accounted for an additional 18% of the variance over and above the other three variables. Results suggest that severity of subcortical disease measured by MRI improves prediction of functional impairment in elderly individuals.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0895-0172
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
404-11
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9116476-Activities of Daily Living,
pubmed-meshheading:9116476-Aged,
pubmed-meshheading:9116476-Depressive Disorder,
pubmed-meshheading:9116476-Female,
pubmed-meshheading:9116476-Frontal Lobe,
pubmed-meshheading:9116476-Humans,
pubmed-meshheading:9116476-Magnetic Resonance Imaging,
pubmed-meshheading:9116476-Male,
pubmed-meshheading:9116476-Middle Aged,
pubmed-meshheading:9116476-Neuropsychological Tests
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pubmed:year |
1996
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pubmed:articleTitle |
Subcortical hyperintensities on MRI and activities of daily living in geriatric depression.
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pubmed:affiliation |
Butler Hospital, Providence, RI 02906, USA.
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pubmed:publicationType |
Journal Article
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