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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1997-4-18
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pubmed:abstractText |
Two hundred and eighty-two patients with birthweights below 2.0 kg were routinely screened for spontaneous development of maximum renal acid stimulation (urine-pH < 5.4). Sixty episodes in 53 patients of incipient late metabolic acidosis (urine pH < 5.4 on 2 consecutive days) were randomly allocated to oral therapy with 2 mmol/kg/day of either NaHCO3 or NaCl for 7 days. All 27 patients on NaHCO3 therapy, but only 15 from 26 patients on NaCl therapy, showed an increase in urine pH values, combined with a relatively high gain in body weight and a tendency to increased N-assimilation. Eleven patients on NaCl therapy showed persistent maximal renal acid stimulation on all 7 days with possibly lower weight gain and no clear change in N-assimilation. Thus, in patients with incipient late metabolic acidosis, NaCl therapy is not as beneficial as NaHCO3 therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0803-5253
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
96-101
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9116434-Acidosis, Renal Tubular,
pubmed-meshheading:9116434-Body Weight,
pubmed-meshheading:9116434-Humans,
pubmed-meshheading:9116434-Hydrogen-Ion Concentration,
pubmed-meshheading:9116434-Infant, Newborn,
pubmed-meshheading:9116434-Infant, Premature, Diseases,
pubmed-meshheading:9116434-Infant, Small for Gestational Age,
pubmed-meshheading:9116434-Prospective Studies,
pubmed-meshheading:9116434-Sodium Bicarbonate,
pubmed-meshheading:9116434-Sodium Chloride
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pubmed:year |
1997
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pubmed:articleTitle |
Alkali therapy versus sodium chloride supplement in low birthweight infants with incipient late metabolic acidosis.
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pubmed:affiliation |
Pediatric Clinic, Dortmund and Research Institute of Child Nutrition, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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