9114415

Source:http://linkedlifedata.com/resource/pubmed/id/9114415

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0012634, umls-concept:C0085294, umls-concept:C0205146, umls-concept:C0243130
pubmed:issue	5
pubmed:dateCreated	1997-8-27
pubmed:abstractText	If the occurrence of hepatitis E virus antibody (anti-HEV) in regions where the disease is not endemic represents infection, rates may be greater in high-risk populations and behavioral correlates may reflect recognized transmission modes. Serum samples from 300 homosexual males, 300 injection drug users (IDUs), and 300 blood donors from Baltimore, Md., were tested for anti-HEV by enzyme immunoassay. Anti-HEV was found in an unexpectedly high percentage of homosexual men (15.9%) and IDUs (23.0%). However, anti-HEV was present in a similar proportion of blood donors (21.3%) (P > 0.05), while hepatitis A, B, and C virus antibodies were more prevalent in the high-risk groups (P < 0.001). Among homosexual men, anti-HEV was not significantly correlated with a history of hepatitis, high-risk sexual practices, or sexually transmitted infections, in contrast to hepatitis A and B antibodies. Among IDUs, anti-HEV was not significantly associated with a history of hepatitis or high-risk drug-using practices, as was found with hepatitis C antibodies. In a setting without endemic hepatitis E disease, there was no evidence that anti-HEV reflected subclinical infection. Until the basis for HEV seroreactivity in such areas is elucidated, anti-HEV results should be interpreted with caution.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/DA-04334, http://linkedlifedata.com/resource/pubmed/grant/DA-08004, http://linkedlifedata.com/resource/pubmed/grant/U01-AI-35042
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/9114415-1346411, http://linkedlifedata.com/resource/pubmed/commentcorrection/9114415-1583332, http://linkedlifedata.com/resource/pubmed/commentcorrection/9114415-1720924, http://linkedlifedata.com/resource/pubmed/commentcorrection/9114415-6243391, http://linkedlifedata.com/resource/pubmed/commentcorrection/9114415-7623656, http://linkedlifedata.com/resource/pubmed/commentcorrection/9114415-7658774, http://linkedlifedata.com/resource/pubmed/commentcorrection/9114415-7797939, http://linkedlifedata.com/resource/pubmed/commentcorrection/9114415-7937861, http://linkedlifedata.com/resource/pubmed/commentcorrection/9114415-8077708, http://linkedlifedata.com/resource/pubmed/commentcorrection/9114415-8096022, http://linkedlifedata.com/resource/pubmed/commentcorrection/9114415-8099641, http://linkedlifedata.com/resource/pubmed/commentcorrection/9114415-8527554
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7505564
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	0095-1137
pubmed:author	pubmed-author:NelsonK EKE, pubmed-author:PurcellR HRH, pubmed-author:SaahA JAJ, pubmed-author:ThomasD LDL, pubmed-author:TsarevS ASA, pubmed-author:VlahovDD, pubmed-author:YarboughP OPO
pubmed:issnType	Print
pubmed:volume	35
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1244-7
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:9114415-Hepatitis E, pubmed-meshheading:9114415-Hepatitis E virus, pubmed-meshheading:9114415-Homosexuality, Male, pubmed-meshheading:9114415-Humans, pubmed-meshheading:9114415-Immunoassay, pubmed-meshheading:9114415-Male, pubmed-meshheading:9114415-Substance Abuse, Intravenous
pubmed:year	1997
pubmed:articleTitle	Seroreactivity to hepatitis E virus in areas where the disease is not endemic.
pubmed:affiliation	Division of Infectious Diseases, Johns Hopkins School of Medicine, Baltimore, Maryland, USA. dthomas@welchlink.welch.jhu.edu
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S.