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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1997-5-7
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pubmed:abstractText |
The HIV-1 nef gene product, thought to interact with mediators of cell signalling, is overexpressed during the restricted HIV-1 infection of human astrocytes. This infection can be reactivated following exposure to tumour necrosis factor (TNF)-alpha. We examined the possibility that Nef alters the TNF-alpha-induced cell signalling in astroglioma cells through the sphingomyelin pathway.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Ceramides,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Gene Products, nef,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Sphingomyelin Phosphodiesterase,
http://linkedlifedata.com/resource/pubmed/chemical/Sphingomyelins,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor AP-1,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/nef Gene Products, Human...
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0269-9370
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
F1-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9110068-Cells, Cultured,
pubmed-meshheading:9110068-Ceramides,
pubmed-meshheading:9110068-DNA, Neoplasm,
pubmed-meshheading:9110068-Enzyme Activation,
pubmed-meshheading:9110068-Gene Products, nef,
pubmed-meshheading:9110068-Glioma,
pubmed-meshheading:9110068-HIV-1,
pubmed-meshheading:9110068-Humans,
pubmed-meshheading:9110068-Hydrolysis,
pubmed-meshheading:9110068-NF-kappa B,
pubmed-meshheading:9110068-Neuroglia,
pubmed-meshheading:9110068-RNA, Messenger,
pubmed-meshheading:9110068-Signal Transduction,
pubmed-meshheading:9110068-Sphingomyelin Phosphodiesterase,
pubmed-meshheading:9110068-Sphingomyelins,
pubmed-meshheading:9110068-Transcription Factor AP-1,
pubmed-meshheading:9110068-Tumor Cells, Cultured,
pubmed-meshheading:9110068-Tumor Necrosis Factor-alpha,
pubmed-meshheading:9110068-nef Gene Products, Human Immunodeficiency Virus
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pubmed:year |
1997
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pubmed:articleTitle |
Interference of HIV-1 Nef in the sphingomyelin transduction pathway activated by tumour necrosis factor-alpha in human glial cells.
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pubmed:affiliation |
Infectious Diseases, CHUL Research Centre, Quebec, Canada.
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pubmed:publicationType |
Journal Article
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