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pubmed-article:9107153pubmed:abstractTextShort-term depletion of plasma tryptophan has been shown to result in depressive relapse in patients with remission of major depression. Positron emission tomography and single photon emission computed tomography studies implicated the dorsolateral prefrontal cortex, orbitofrontal cortex, thalamus, and caudate nucleus in the pathogenesis of depression. The purpose of this study was to measure cerebral metabolic correlates of tryptophan depletion-induced depressive relapse.lld:pubmed
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pubmed-article:9107153pubmed:articleTitlePositron emission tomography measurement of cerebral metabolic correlates of tryptophan depletion-induced depressive relapse.lld:pubmed
pubmed-article:9107153pubmed:affiliationDepartment of Psychiatry, Yale University School of Medicine, New Haven, Conn, USA.lld:pubmed
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