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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1997-7-3
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pubmed:abstractText |
Membranes are used to guide the repopulation of defects by preferred cells and to achieve a specific healing effect. The collagen membrane studied, Bio-Gide, was developed particularly for periodontal, peri-implant applications or to improve the ossification of bone defects of any origin. Bio-Gide is a bilayer membrane; one compact and smooth layer is covered by a particularly dense film, designed to prevent the invasion of soft tissue in a membrane-protected bone defect. The other, rough side of Bio-Gide must be placed towards the bone defect in order to make bone ingrowth possible. As a prerequisite for its therapeutic use in humans, the collagen matrix must be devoid of major immunogenicity. The immunological response to the membrane material was analysed in rabbits. Later, a clinical prospective study provided information about the bone regeneration effect under the Bio-Gide membrane inserted in six patients selected at random. The immune response to the collagen membrane Bio-Gide and the bone healing was tested in these patients when undergoing oral surgery.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0142-9612
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
535-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9105592-Animals,
pubmed-meshheading:9105592-Biocompatible Materials,
pubmed-meshheading:9105592-Cattle,
pubmed-meshheading:9105592-Collagen,
pubmed-meshheading:9105592-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:9105592-Humans,
pubmed-meshheading:9105592-Membranes, Artificial,
pubmed-meshheading:9105592-Molar,
pubmed-meshheading:9105592-Osteogenesis,
pubmed-meshheading:9105592-Rabbits,
pubmed-meshheading:9105592-Random Allocation,
pubmed-meshheading:9105592-Reproducibility of Results,
pubmed-meshheading:9105592-Surgery, Oral,
pubmed-meshheading:9105592-Swine,
pubmed-meshheading:9105592-Wound Healing
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pubmed:year |
1997
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pubmed:articleTitle |
Preclinical and clinical studies of a collagen membrane (Bio-Gide).
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pubmed:affiliation |
Klinik und Poliklinik für Kieferchirurgie, Ludwig Maximilians Universität, München, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study
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