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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1997-4-17
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pubmed:abstractText |
Current therapy strategies for localized neuroblastomas are mainly based on surgical procedures. In our analysis of 657 patients with localized neuroblastomas (mean follow-up: 6.2 years), the extent of surgical removal predicted outcome (complete resection: 0.91 +/- 0.02; partial resection: 0.79 +/- 0.04; biopsy 0.49 +/- 0.11). But for stage 2/II (0.96 +/- 0.02 vs. 0.91 +/- 0.06) and stage 3/III tumors (0.82 +/- 0.04 vs. 0.78 +/- 0.04) no difference in survival was seen between complete and partial resection of the primary tumor. Outcome was worse in stage 3/III patients who underwent biopsy only (0.48 +/- 0.11). Complications were seen after 20% of 853 surgical procedures, sometimes requiring second operations (n = 29) or leading to death (n = 11). Infants were especially at risk from complications: eight infants died of complications. Looking at these results, extended surgical procedures should be avoided to minimize the risk for the patient.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0942-2854
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
113
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1062-9
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pubmed:dateRevised |
2008-2-20
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pubmed:meshHeading |
pubmed-meshheading:9101782-Child,
pubmed-meshheading:9101782-Child, Preschool,
pubmed-meshheading:9101782-Female,
pubmed-meshheading:9101782-Follow-Up Studies,
pubmed-meshheading:9101782-Humans,
pubmed-meshheading:9101782-Infant,
pubmed-meshheading:9101782-Male,
pubmed-meshheading:9101782-Neoplasm Recurrence, Local,
pubmed-meshheading:9101782-Neoplasm Staging,
pubmed-meshheading:9101782-Neuroblastoma,
pubmed-meshheading:9101782-Prognosis,
pubmed-meshheading:9101782-Survival Rate
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pubmed:year |
1996
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pubmed:articleTitle |
[Risk and benefits of surgical interventions in localized neuroblastoma--experiences from cooperative studies in Germany].
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pubmed:affiliation |
Universitätskinderklinik, Universität zu Köln.
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pubmed:publicationType |
Journal Article,
English Abstract
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