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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1997-5-12
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pubmed:databankReference |
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pubmed:abstractText |
FKBP-rapamycin associated protein (FRAP) is a phosphatidylinositol kinase (PIK)-related kinase implicated in the inhibition of progression through G1 of the cell cycle. The PIK-related kinases are a growing family of proteins involved in cell-cycle checkpoints, DNA repair and recombination. We have mapped the human FRAP gene to chromosome 1p36.2, a region consistently deleted in neuroblastomas.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0340-6717
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
99
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
547-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:9099849-Base Sequence,
pubmed-meshheading:9099849-Carrier Proteins,
pubmed-meshheading:9099849-Chromosome Mapping,
pubmed-meshheading:9099849-Chromosomes, Human, Pair 1,
pubmed-meshheading:9099849-Humans,
pubmed-meshheading:9099849-Immunophilins,
pubmed-meshheading:9099849-In Situ Hybridization, Fluorescence,
pubmed-meshheading:9099849-Molecular Sequence Data,
pubmed-meshheading:9099849-Phosphotransferases (Alcohol Group Acceptor),
pubmed-meshheading:9099849-TOR Serine-Threonine Kinases
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pubmed:year |
1997
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pubmed:articleTitle |
The human gene encoding FKBP-rapamycin associated protein (FRAP) maps to chromosomal band 1p36.2.
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pubmed:affiliation |
Molecular Medicine Unit, University of Leeds, St. James's University Hospital, UK. desnl@stjames.leeds.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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