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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9056
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pubmed:dateCreated |
1997-4-25
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pubmed:abstractText |
Community studies with 1-3 years of follow-up have reported four to five times higher mortality in HIV-2-infected than in uninfected adults. In a cohort study of HIV-1, an increasing difference in mortality rates of HIV-1-infected and uninfected individuals is expected over time, because of rising mortality with advancing HIV-1 infection. We therefore investigated long-term survival of HIV-2-infected adults.
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pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Acquired Immunodeficiency Syndrome,
http://linkedlifedata.com/resource/pubmed/keyword/Africa,
http://linkedlifedata.com/resource/pubmed/keyword/Africa South Of The Sahara,
http://linkedlifedata.com/resource/pubmed/keyword/Demographic Factors,
http://linkedlifedata.com/resource/pubmed/keyword/Developing Countries,
http://linkedlifedata.com/resource/pubmed/keyword/Differential Mortality,
http://linkedlifedata.com/resource/pubmed/keyword/Diseases,
http://linkedlifedata.com/resource/pubmed/keyword/Guinea-bissau,
http://linkedlifedata.com/resource/pubmed/keyword/Hiv Infections,
http://linkedlifedata.com/resource/pubmed/keyword/Length Of Life,
http://linkedlifedata.com/resource/pubmed/keyword/Measurement,
http://linkedlifedata.com/resource/pubmed/keyword/Mortality,
http://linkedlifedata.com/resource/pubmed/keyword/Population,
http://linkedlifedata.com/resource/pubmed/keyword/Population Characteristics,
http://linkedlifedata.com/resource/pubmed/keyword/Population Dynamics,
http://linkedlifedata.com/resource/pubmed/keyword/Portuguese Speaking Africa,
http://linkedlifedata.com/resource/pubmed/keyword/Prevalence,
http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology,
http://linkedlifedata.com/resource/pubmed/keyword/Research Report,
http://linkedlifedata.com/resource/pubmed/keyword/Survivorship,
http://linkedlifedata.com/resource/pubmed/keyword/Urban Population,
http://linkedlifedata.com/resource/pubmed/keyword/Viral Diseases,
http://linkedlifedata.com/resource/pubmed/keyword/Western Africa
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0140-6736
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
29
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pubmed:volume |
349
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
911-4
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pubmed:dateRevised |
2006-11-15
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pubmed:otherAbstract |
PIP: While HIV-2 infection can lead to AIDS, it takes longer than HIV-1 to induce immunosuppression and AIDS, it is less transmissible, and it is associated with lower mortality than HIV-1 infection. 1329 people from among 100 houses in Guinea-Bissau participated in a 1987 study of HIV seroprevalence in their community. 8.9% of the family members older than age 14 years were infected with HIV-2, as well as 0.6% of the 677 children, but no one was infected with HIV-1. All subjects enrolled in the 1987 study over age 14 were followed up with serological surveys in 1989 and 1992, with their survival assessed in 1995. HIV-2 associated mortality did not increase over time and mortality in HIV-2-infected adults was only twice as high as that among uninfected individuals. In the majority of adults, HIV-2 has no effect upon survival. The difference in mortality between the infected and the uninfected was greater for adults under age 45 years than for older people. Furthermore, HIV-2-infected individuals living with an infected spouse had significantly higher mortality than those living with an uninfected spouse.
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pubmed:meshHeading |
pubmed-meshheading:9093252-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:9093252-Adolescent,
pubmed-meshheading:9093252-Adult,
pubmed-meshheading:9093252-Age Factors,
pubmed-meshheading:9093252-Aged,
pubmed-meshheading:9093252-Cohort Studies,
pubmed-meshheading:9093252-Female,
pubmed-meshheading:9093252-Follow-Up Studies,
pubmed-meshheading:9093252-Guinea-Bissau,
pubmed-meshheading:9093252-HIV Infections,
pubmed-meshheading:9093252-HIV-2,
pubmed-meshheading:9093252-Humans,
pubmed-meshheading:9093252-Incidence,
pubmed-meshheading:9093252-Male,
pubmed-meshheading:9093252-Middle Aged,
pubmed-meshheading:9093252-Proportional Hazards Models,
pubmed-meshheading:9093252-Survival Analysis,
pubmed-meshheading:9093252-Survival Rate,
pubmed-meshheading:9093252-Time Factors,
pubmed-meshheading:9093252-Urban Population
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pubmed:year |
1997
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pubmed:articleTitle |
9-year HIV-2-associated mortality in an urban community in Bissau, west Africa.
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pubmed:affiliation |
Department of Epidemiology Research, Danish Epidemiology Science Centre.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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