Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1997-8-15
pubmed:abstractText
Peroxisomal oxidation was measured in mouse brain homogenate by adding cyanide to the test tube (which inhibits mitochondrial oxidation). Eighteen-carbon fatty acids (saturated, monounsaturated and polyunsaturated) were oxidized by brain peroxisomes. At nearly all ages, oxidation of oleic acid was higher (about 2 fold) than oxidation of other eighteen-carbon fatty acids. In contrast to other fatty acids, stearic acid oxidation decreased regularly up to weaning (6 fold) and was stable thereafter. Oleic acid oxidation increased up to weaning, decreased during development up to day 70 and remained subsequently nearly stable. Linoleic acid and alpha-linolenic acid oxidation increased up to weaning, decreased up to day 105 and was nearly stable thereafter. Alpha-linolenic acid oxidation about was two fold lower than linoleic acid oxidation. Interestingly, peroxisomal oxidation for all fatty acids examined declined during aging, between day 365 and day 450.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1039-9712
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
461-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Alterations in eighteen-carbon saturated, monounsaturated and polyunsaturated fatty acid peroxisomal oxidation in mouse brain during development and aging.
pubmed:affiliation
INSERM U 26, Hopital Fernand Widal, Paris.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't