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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1997-5-13
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pubmed:abstractText |
Although progress in our understanding of T channels and their physiological role has been slower than with other Ca2+ channels, it was clear during this two-day workshop that interest and research in the field remain very intense. Advances have been hampered by many factors: small current amplitude, lack of pharmacological tools, apparent heterogeneity, and lack of a cloned channel. Nevertheless, many interesting roles for T channels have been described, which point to a generally subtle modulatory action. Furthermore, recent results suggest that the above barriers might soon be abolished: new pharmacological tools (mibefradil and newer generation compounds) with T-channel selectivity are being developed and many groups claim to be close to cloning a T channel.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0165-6147
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37-42
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9090306-Animals,
pubmed-meshheading:9090306-Calcium Channel Blockers,
pubmed-meshheading:9090306-Calcium Channels,
pubmed-meshheading:9090306-Cell Communication,
pubmed-meshheading:9090306-Cell Division,
pubmed-meshheading:9090306-Cloning, Molecular,
pubmed-meshheading:9090306-Electrophysiology,
pubmed-meshheading:9090306-Exons,
pubmed-meshheading:9090306-Humans,
pubmed-meshheading:9090306-Rats
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pubmed:year |
1997
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pubmed:articleTitle |
Low-voltage-activated T-type Ca2+ channels.
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pubmed:affiliation |
Sundgau Medical Writers, Habsheim, France.
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pubmed:publicationType |
Congresses
|