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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1997-5-30
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pubmed:abstractText |
The effect of nipradilol solution (KT-210) on aqueous flow was evaluated using fluorophotometry in 10 patients (6 primary open-angle glaucoma and 4 ocular hypertension) treated with timolol for more than one month. A single dose of 0.5% timolol was instilled into both eyes at 8 AM, and 0.25% KT-210 or placebo was instilled into both right and left eye at 11 AM; the treated eye was chosen randomly. Aqueous flow was measured every hour from 9 AM to 3 PM. There was no significant difference in pretreatment aqueous flow between the two eyes; 1.98 +/- 0.53 microliters/min in the KT-210 treated eyes, and 1.98 +/- 0.76 microliters/min in the placebo treated eyes. The flow measured 1 to 4 hours after KT-210 instillation was 1.66 +/- 0.69 microliters/min, 2.23 +/- 1.02 microliters/min, 2.20 +/- 0.67 microliters/min, and 1.68 +/- 0.64 microliters/min, respectively. This flow did not differ significantly from the flow in the placebo treated eyes (1.83 +/- 0.86 microliters/min, 1.79 +/- 0.69 microliters/min, 2.26 +/- 0.58 microliters/min, and 1.84 +/- 0.32 microliters/min).
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic alpha-Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic beta-Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/K 351,
http://linkedlifedata.com/resource/pubmed/chemical/Propanolamines,
http://linkedlifedata.com/resource/pubmed/chemical/Timolol
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0029-0203
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
252-6
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pubmed:dateRevised |
2011-7-28
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pubmed:meshHeading |
pubmed-meshheading:9086746-Adrenergic alpha-Antagonists,
pubmed-meshheading:9086746-Adrenergic beta-Antagonists,
pubmed-meshheading:9086746-Aqueous Humor,
pubmed-meshheading:9086746-Female,
pubmed-meshheading:9086746-Glaucoma,
pubmed-meshheading:9086746-Glaucoma, Open-Angle,
pubmed-meshheading:9086746-Humans,
pubmed-meshheading:9086746-Male,
pubmed-meshheading:9086746-Middle Aged,
pubmed-meshheading:9086746-Propanolamines,
pubmed-meshheading:9086746-Timolol
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pubmed:year |
1997
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pubmed:articleTitle |
[Effect of nipradilol on aqueous flow in glaucoma patients treated with timolol].
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pubmed:affiliation |
Department of Ophthalmology, Faculty of Medicine, University of Ryukyu, Japan.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract,
Randomized Controlled Trial
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