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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1997-4-2
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pubmed:abstractText |
Baeyer-Villiger monooxygenases (BVMOs) are enzymes able to perform highly regio-plus steroselective nucleophilic and electrophilic biooxygenations on various substrates. The resultant chiral products (lactones and sulfoxides) can be valuable for the chemoenzymatic synthesis of a wide range of useful compounds. Recent studies have provided a number of alternative active-site models that attempt to explain the exquisite and unusual selectivity of BVMOs. This article reviews some of the established applications, and considers the merits of the various predictive models.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
B
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0167-7799
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
55-62
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9081299-Amino Acid Sequence,
pubmed-meshheading:9081299-Binding Sites,
pubmed-meshheading:9081299-Flavoproteins,
pubmed-meshheading:9081299-Kinetics,
pubmed-meshheading:9081299-Macromolecular Substances,
pubmed-meshheading:9081299-Mixed Function Oxygenases,
pubmed-meshheading:9081299-Molecular Sequence Data,
pubmed-meshheading:9081299-NAD,
pubmed-meshheading:9081299-NADP,
pubmed-meshheading:9081299-Oxygenases,
pubmed-meshheading:9081299-Substrate Specificity
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pubmed:year |
1997
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pubmed:articleTitle |
Structural studies and synthetic applications of Baeyer-Villiger monooxygenases.
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pubmed:affiliation |
Department of Biological Sciences, University of Exeter, Devon, UK. A.J.Willetts@exeter.ac.uk
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pubmed:publicationType |
Journal Article,
Comparative Study,
Review
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