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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1997-6-5
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pubmed:abstractText |
Okadaic acid, the main toxin of the diarrhoetic shellfish poisoning (DSP) group, shows high cytotoxicity to Buffalo green monkey (BGM) kidney cell cultures after different times according to concentration. A rapid method of detecting the presence of okadaic acid and related compounds in contaminated mussels by means of a cytotoxicity test is presented. The method is based on direct microscopic observation of toxin-induced morphological changes in BGM cell cultures. A high correlation (r = 0.950; P < 0.001) was found between the official mouse bioassay and the cytotoxicity test conducted on naturally contaminated samples of Mytilus galloprovincialis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0041-0101
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
223-30
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:9080579-Animals,
pubmed-meshheading:9080579-Bivalvia,
pubmed-meshheading:9080579-Cercopithecus aethiops,
pubmed-meshheading:9080579-Culture Techniques,
pubmed-meshheading:9080579-Injections, Intraperitoneal,
pubmed-meshheading:9080579-Kidney,
pubmed-meshheading:9080579-Marine Toxins,
pubmed-meshheading:9080579-Mice,
pubmed-meshheading:9080579-Okadaic Acid
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pubmed:year |
1997
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pubmed:articleTitle |
A rapid tissue culture assay for the detection of okadaic acid and related compounds in mussels.
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pubmed:affiliation |
Reparto Igiene delle Technologie Alimentari Laboratorio Alimenti, Istituto Superiore di Sanità, Roma, Italy.
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pubmed:publicationType |
Journal Article
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