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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1997-5-27
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pubmed:abstractText |
The analysis of gene expression patterns in the neural plate and neural tube of the embryonic mouse forebrain shows that, at its earliest stages, the neuroepithelium is subdivided into molecularly distinct domains. Here, and in previous publications, we provide evidence that the patterns of gene expression can be related to primary morphogenetic processes that organize the histological primordia of the embryonic central nervous system into longitudinal and transverse domains. Longitudinal domains are generated by dorsoventral patterning signals produced by the axial mesendoderm and nonneural ectoderm. Transverse domains (proneuromeres and neuromeres) expressing distinct combinations of genes are present in the neural plate and neural tube.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Distal-less homeobox proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Tes protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors
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pubmed:status |
MEDLINE
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pubmed:issn |
0378-5866
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
88-96
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9078438-Animals,
pubmed-meshheading:9078438-Axons,
pubmed-meshheading:9078438-DNA-Binding Proteins,
pubmed-meshheading:9078438-Embryo, Mammalian,
pubmed-meshheading:9078438-Gene Expression,
pubmed-meshheading:9078438-Genes, Homeobox,
pubmed-meshheading:9078438-Homeodomain Proteins,
pubmed-meshheading:9078438-Mice,
pubmed-meshheading:9078438-Mice, Inbred Strains,
pubmed-meshheading:9078438-Neural Pathways,
pubmed-meshheading:9078438-Prosencephalon,
pubmed-meshheading:9078438-Transcription Factors
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pubmed:year |
1997
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pubmed:articleTitle |
Patterns of gene expression in the neural plate and neural tube subdivide the embryonic forebrain into transverse and longitudinal domains.
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pubmed:affiliation |
Nina Ireland Laboratory of Developmental Neurobiology, University of California, San Francisco 94143-0984, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
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