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pubmed-article:9074710pubmed:abstractTextInjury stimulates smooth muscle cell (SMC) migration and proliferation by mechanisms that are incompletely understood. Surgical preparative injury is an important determinant of neointimal thickening in human saphenous vein bypass grafts. We investigate here whether basement-membrane-degrading metalloproteinases (MMPs) are stimulated by surgical preparation and culturing of human saphenous veins in organ culture.lld:pubmed
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pubmed-article:9074710pubmed:articleTitleSurgical preparative injury and neointima formation increase MMP-9 expression and MMP-2 activation in human saphenous vein.lld:pubmed
pubmed-article:9074710pubmed:affiliationBristol Heart Institute, University of Bristol, UK.lld:pubmed
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