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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1997-4-9
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pubmed:abstractText |
Injury stimulates smooth muscle cell (SMC) migration and proliferation by mechanisms that are incompletely understood. Surgical preparative injury is an important determinant of neointimal thickening in human saphenous vein bypass grafts. We investigate here whether basement-membrane-degrading metalloproteinases (MMPs) are stimulated by surgical preparation and culturing of human saphenous veins in organ culture.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
447-59
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9074710-Blotting, Western,
pubmed-meshheading:9074710-Collagenases,
pubmed-meshheading:9074710-Coronary Artery Bypass,
pubmed-meshheading:9074710-Enzyme Activation,
pubmed-meshheading:9074710-Gelatinases,
pubmed-meshheading:9074710-Humans,
pubmed-meshheading:9074710-Immunohistochemistry,
pubmed-meshheading:9074710-In Situ Hybridization,
pubmed-meshheading:9074710-Matrix Metalloproteinase 2,
pubmed-meshheading:9074710-Matrix Metalloproteinase 9,
pubmed-meshheading:9074710-Metalloendopeptidases,
pubmed-meshheading:9074710-Muscle, Smooth, Vascular,
pubmed-meshheading:9074710-Organ Culture Techniques,
pubmed-meshheading:9074710-Saphenous Vein
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pubmed:year |
1997
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pubmed:articleTitle |
Surgical preparative injury and neointima formation increase MMP-9 expression and MMP-2 activation in human saphenous vein.
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pubmed:affiliation |
Bristol Heart Institute, University of Bristol, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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