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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1997-6-5
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pubmed:abstractText |
Microsomal lauric acid hydroxylation and fatty acid peroxisomal beta-oxidation were studied in hepatic subcellulant preparations from streptozotocin-induced diabetic and diabetic insulin-treated rats. 2. The liver microsomes of the streptozotocin diabetic rats displayed a similar activity to hydroxylate lauric acid as the control microsomes. 3. Diabetic insulin-treated rats showed lower (omega 1) and omega-lauric acid hydroxylase activities than diabetic and control rats. 4. Streptozotocin-induced diabetes and diabetic insulin-treated rats exhibited no significant changes on peroxisomal palmitoyl CoA beta-oxidation compared to the control rats. 5. Both microsomal and peroxisomal fatty acid oxidation responded in a similar way in this model of experimental diabetes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0306-3623
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
361-4
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:9068973-Animals,
pubmed-meshheading:9068973-Body Weight,
pubmed-meshheading:9068973-Cytochrome P-450 Enzyme System,
pubmed-meshheading:9068973-Diabetes Mellitus, Experimental,
pubmed-meshheading:9068973-Insulin,
pubmed-meshheading:9068973-Lauric Acids,
pubmed-meshheading:9068973-Liver,
pubmed-meshheading:9068973-Male,
pubmed-meshheading:9068973-Microbodies,
pubmed-meshheading:9068973-Microsomes, Liver,
pubmed-meshheading:9068973-Organ Size,
pubmed-meshheading:9068973-Oxidation-Reduction,
pubmed-meshheading:9068973-Rats,
pubmed-meshheading:9068973-Rats, Wistar,
pubmed-meshheading:9068973-Streptozocin
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pubmed:year |
1997
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pubmed:articleTitle |
Microsomal and peroxisomal fatty acid oxidation in streptozotocin diabetic rat liver.
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pubmed:affiliation |
Department of Biochemistry, Faculty of Medicine, University of Chile, Santiago, Chile.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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