Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1997-5-9
pubmed:abstractText
Results are presented from an in vivo study of human skin in which a zig-zag surface coil together with a three-pulse Fourier Series Window (FSW) protocol have been used to obtain minimally contaminated 31P skin spectra of the posterior calf. Phantom experiments indicate that while the fall-off in the B1 field profile of the zig-zag surface coil is superior to conventional surface coil designs, it is still not sufficient on its own to reduce muscle signal contamination to acceptable levels in human studies. The additional spatial localization required is provided by the FSW, which reduces signal contamination to less than 30% of the total signal collected. In a study of 18 normal controls the measured pH was found to be relatively high (7.39 +/- 0.08), while the ratios of skin PCr/ beta-ATP (1.04 +/- 0.35) and PCr/Pi (1.67 +/- 0.4) were found to be low compared with that of skeletal muscle. In addition, substantial signal from phosphomonoesters and phosphodiesters were also observed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0952-3480
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
195-200
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
31P NMR studies of human skin using a modified zig-zag surface coil.
pubmed:affiliation
Nuffield Department of Surgery, John Radcliffe Hospital, Headington, Oxford, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't