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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1997-5-27
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pubmed:abstractText |
The persistent activity of moxidectin topically administered at the dose rate of 0.5 mg kg-1 bodyweight was evaluated against experimental nematode infection in 30 calves randomly allocated to six groups. Five groups were treated on days -42, -35, -28, -21 and -14. The 6th group remained untreated as a control. On Day 0, the calves were infected experimentally with 1000 Dictyocaulus viviparus and 50,000 Ostertagia ostertagi larvae and killed 3 weeks later. The formulation of moxidectin showed excellent activity against both parasites for up to 5 weeks (> 99%). Six weeks after treatment the reduction in the number of D. viviparus was still high (> 90%). No adverse reactions to moxidectin were observed in any of the animals.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0304-4017
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
187-90
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9066064-Administration, Topical,
pubmed-meshheading:9066064-Animals,
pubmed-meshheading:9066064-Anthelmintics,
pubmed-meshheading:9066064-Anti-Bacterial Agents,
pubmed-meshheading:9066064-Cattle,
pubmed-meshheading:9066064-Cattle Diseases,
pubmed-meshheading:9066064-Dictyocaulus Infections,
pubmed-meshheading:9066064-Larva,
pubmed-meshheading:9066064-Macrolides,
pubmed-meshheading:9066064-Ostertagiasis,
pubmed-meshheading:9066064-Time Factors
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pubmed:year |
1997
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pubmed:articleTitle |
Persistent efficacy of topical moxidectin against Dictyocaulus viviparus and Ostertagia ostertagi.
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pubmed:affiliation |
INRA Station de Pathologie Aviaire et de Parasitologie, Unité d'Helminthologie, Nouzilly, France.
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pubmed:publicationType |
Journal Article
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