Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1997-7-18
|
pubmed:abstractText |
A physiological dose of melatonin (0.5 mg) or placebo was given at bedtime to night shift workers (n = 21) for seven days, and endogenous melatonin profiles were measured on the eighth day. The amplitude of endogenous melatonin secretion was unchanged by treatment. Also, a melatonin treatment trial using a 50 mg daily bedtime dose for 37 days to a blind subject resulted in no change in the endogenous melatonin profile. We conclude that circulating melatonin can shift the phase, but does not alter the amplitude, of pineal melatonin secretion.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0742-3098
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
42-4
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:9062869-Adult,
pubmed-meshheading:9062869-Blindness,
pubmed-meshheading:9062869-Female,
pubmed-meshheading:9062869-Humans,
pubmed-meshheading:9062869-Male,
pubmed-meshheading:9062869-Melatonin,
pubmed-meshheading:9062869-Middle Aged,
pubmed-meshheading:9062869-Photoperiod,
pubmed-meshheading:9062869-Work Schedule Tolerance
|
pubmed:year |
1997
|
pubmed:articleTitle |
The amplitude of endogenous melatonin production is not affected by melatonin treatment in humans.
|
pubmed:affiliation |
Department of Psychiatry and Neurology, Asahikawa Medical College, Japan.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Controlled Clinical Trial
|