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rdf:type |
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lifeskim:mentions |
umls-concept:C0006675,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0036226,
umls-concept:C0086418,
umls-concept:C0205409,
umls-concept:C0243144,
umls-concept:C0596981,
umls-concept:C1140999,
umls-concept:C1280500,
umls-concept:C2355627
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pubmed:issue |
1
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pubmed:dateCreated |
1997-3-28
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pubmed:abstractText |
There has been debate regarding the level of sarcoplasmic reticulum (SR) Ca2+ ATPase protein in heart failure. We have used the SR Ca2+ ATPase inhibitor thapsigargin to investigate the functional contribution of this uptake system to contraction and relaxation in myocytes from failing and non-failing human ventricle.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
88-97
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:9059532-Aged,
pubmed-meshheading:9059532-Calcium,
pubmed-meshheading:9059532-Calcium-Transporting ATPases,
pubmed-meshheading:9059532-Cell Size,
pubmed-meshheading:9059532-Cells, Cultured,
pubmed-meshheading:9059532-Electric Stimulation,
pubmed-meshheading:9059532-Female,
pubmed-meshheading:9059532-Heart Failure,
pubmed-meshheading:9059532-Humans,
pubmed-meshheading:9059532-Male,
pubmed-meshheading:9059532-Middle Aged,
pubmed-meshheading:9059532-Myocardial Contraction,
pubmed-meshheading:9059532-Myocardium,
pubmed-meshheading:9059532-Sarcoplasmic Reticulum,
pubmed-meshheading:9059532-Thapsigargin
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pubmed:year |
1997
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pubmed:articleTitle |
Effects of inhibition of sarcoplasmic reticulum calcium uptake on contraction in myocytes isolated from failing human ventricle.
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pubmed:affiliation |
National Heart and Lung Institute, Imperial College, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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